منابع مشابه
New drugs. Hypnotics and anxiolytics.
Anxiolytics Anxiety is a normal reaction but when severe and disabling it becomes pathological. Phobias are distinguished from anxiety, and some classifications also separate panic attacks. Patients should be assessed carefully to detect associated problems in their lives and to seek evidence of underlying illness, such as depression and organic brain disease, that may present as anxiety. Conve...
متن کاملSleep and the Modern Hypnotics
Although the phenomena of sleep have been well known for a considerable time, the proximate factors in its causation are still but little understood. The phenomena are : A diminution of metabolic processes all over the body ; a relaxation of the voluntary muscles ; a diminution in the secretory activity of all glandular structures ; a slowing of the heart, and a slowing and deepening of respira...
متن کاملThiazolodiazepines: New Ultra-short Acting Hypnotics
The synthesis and hypnotic evaluation of a new generation of thiazolo[3,2-a][1,3]diazepine analogs are described. Those compounds exhibit potent in vivo activities as ultra-short acting hypnotics. Background of the Invention Surgical procedures require the administration of several intravenous drugs to ensure hypnosis, analgesia, relaxation and control of visceral reflex responses. The use of i...
متن کاملZopiclone, a third generation of hypnotics.
Many years ago now the benzodiaze-pines began to replace the barbiturates, but, when we think about this change and remember that the barbiturates were probably being used in unnecessarily high doses, the therapeutic advantage of the benzodiaze-pines may not have been so great as it appeared at the time. The major advance was that of increased safety in overdosage. Initially, the benzodiazepine...
متن کاملBenzodiazepine hypnotics increase heart rate during sleep.
The cardiovascular effects of benzodiazepines administered intravenously as preoperative sedatives have received considerable study, but sleep laboratory research on benzodiazepines administered orally as hypnotics has not focused on assessment of cardiovascular changes. Analysis of heart rate (HR) data collected in sleep laboratory studies on the effects of 0.5 mg of triazolam (Halcion) and 30...
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ژورنال
عنوان ژورنال: BMJ
سال: 1970
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5708.539-a